Learning objectives:

• Describe ischemia and acute coronary syndrome
• Describe the Fourth Universal Definition of myocardial infarction (2018)
• Describe the biochemistry of cardiac troponin
• Describe cardiac troponin assays and the standardization of cardiac troponin testing
• Describe the determination of 99th percentile upper reference limits of cardiac troponin
• Describe the clinical use of cardiac troponin