Laboratory Genomics

INHERITED CANCERS I: MECHANISMS AND GENETIC INSTABILITY SYNDROMES (ADVANCED)

Learning Lab Advanced

Author information
Jude M. Abadie, PhD, DABCC(C&T), FAACC
Dr Abadie disclosed no conflict of interest

Learning objectives:

  • List characteristics of inherited cancers that differentiate them from sporadic cancers
  • Describe epigenetic changes that can lead to inherited cancers
  • Explain roles for caretaker and gatekeeper genes in the pathogenesis of inherited cancers.