Transfusion Medicine

PLASMA PRODUCTS AND DERIVATIVES (MLS)

Learning Lab for Medical Laboratory Scientists

Author information
Kerry O'Brien, MD
Dr O'Brien disclosed salary/consultant fees from DynaMed

Learning objectives:

  • Detail the various plasma products available in the United States for transfusion
  • Detail the indications for plasma transfusion in adult and pediatric patients
  • Discuss the dosing of plasma products in adult and pediatric patients when used to correct multiple factor deficiencies
  • Discuss the indications for cryoprecipitate transfusion in adult and pediatric patients
  • Detail how cryoprecipitate is processed from whole blood collections
  • Explain how cryoprecipitate is dosed when used for fibrinogen replacement in adult and pediatric patients
  • Discuss the clinical indications for infusion of the most common plasma derivatives to include albumin, intravenous immune globulin (IVIG), prothrombin complex concentrates, antithrombin III, von Willebrand factor, and fibrinogen concentrate
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