Learning objectives:

• Detail the various plasma products available in the United States for transfusion
• Detail the indications for plasma transfusion in adult and pediatric patients
• Discuss the dosing of plasma products in adult and pediatric patients when used to correct multiple factor deficiencies
• Discuss the indications for cryoprecipitate transfusion in adult and pediatric patients
• Detail how cryoprecipitate is processed from whole blood collections
• Explain how cryoprecipitate is dosed when used for fibrinogen replacement in adult and pediatric patients
• Discuss the clinical indications for infusion of the most common plasma derivatives to include albumin, intravenous immune globulin (IVIG), prothrombin complex concentrates, antithrombin III, von Willebrand factor, and fibrinogen concentrate