Learning objectives:

• Describe basic principles of apheresis technology
• Detail replacement fluids and anticoagulation
• Identify current guidelines for therapeutic apheresis
• Understand periprocedural clinical considerations
• Know plasma exchange (plasmapheresis)
• Explain plasma exchange in idiopathic thrombotic thrombocytopenic purpura (TTP)
• Understand plasma exchange in Myasthenia Gravis
• Describe red cell exchange (Erythrocytapheresis)
• Describe red cell exchange in sickle cell disease
• Identify white blood cell depletion (Leukocytapheresis)
• Identify platelet depletion (Thrombocytapheresis)